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Impact of COVID-19 in Children with Chronic Lung Diseases
Valentina Agnese Ferraro1, Stefania Zanconato1, Silvia Carraro1
1Unit of Pediatric Allergy and Respiratory Medicine, Women's and Children's Health Department, University of Padova, 35128 Padova, Italy.
Insights
Children with chronic lung disease (CLD) face increased COVID-19 risks, but may also have protective factors. The pandemic
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, has impacted global health.
- Children with chronic lung diseases (CLD) may be at increased risk.
- Understanding COVID-19's impact on this vulnerable pediatric population is crucial.
Purpose of the Study:
- To review the impact of COVID-19 on children with CLD.
- To analyze potential risk and protective factors in this population.
- To examine the psychological effects of pandemic restrictions on affected children.
Main Methods:
- A narrative review of existing literature.
- Searched MEDLINE/PubMed for studies on COVID-19/SARS-CoV-2 and pediatric chronic lung diseases.
- Included studies focused on children aged 0-18 years.
Main Results:
- COVID-19 is typically mild in children, but CLD can be a risk factor if severe or poorly controlled.
- Preventive measures and asthma management (inhaled corticosteroids, T2 inflammation) may offer protection.
- Pandemic-related restrictions significantly impacted the psychological well-being of children with CLD.
Conclusions:
- While CLD can increase COVID-19 severity in children, certain factors may mitigate risk.
- The psychological impact of the pandemic on children with CLD requires attention.
- Further research is needed to fully understand COVID-19's long-term effects on pediatric CLD.
Background:
since December 2019, the world has become victim of the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The aim of our narrative review is to analyze the impact of COVID-19 in children suffering from chronic lung disease (CLD).
Methods:
we searched the MEDLINE/Pubmed database using the terms "SARS-CoV-2" or "COVID-19" or "Coronavirus Diseases 2019"; AND "chronic lung diseases" or "chronic respiratory diseases" or "asthma" or "cystic fibrosis" or "primary ciliary dyskinesia" or "bronchopulmonary dysplasia"; and limiting the search to the age range 0-18 years.
Results And Conclusions:
although COVID-19 rarely presents with a severe course in children, CLD may represent a risk factor; especially when already severe or poorly controlled before SARS-CoV-2 infection. On the other hand, typical features of children with CLD (e.g., the accurate adoption of prevention measures, and, in asthmatic patients, the regular use of inhaled corticosteroids and T2 inflammation) might have a role in preventing SARS-CoV-2 infection. Moreover, from a psychological standpoint, the restrictions associated with the pandemic had a profound impact on children and adolescents with CLD.
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