Related Experiment Video
Updated: Aug 28, 2025

Real-Time Void Spot Assay
Published on: February 10, 2023
Predictive Values of Nocturia and Its Voiding Frequency on the Aging Males' Symptoms
John Wai-Man Yuen1, Ivy Yuen-Ping Wong1, Peter Ka-Fung Chiu2
1School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Background:
The link between nocturia and aging male symptoms (AMS) has not been scientifically established. This study aimed to measure the degree of severity of AMS that impacts health-related quality of life (HRQoL) in adult males living with nocturia and to determine the predictive values of nocturnal factors on AMS.
Methods:
This is an extended analysis of new data collected by using the Hong Kong Traditional AMS (HK-AMS) scale and the Cantonese version of the Pittsburgh Sleep Quality Index (PSQI) in a recently published cross-sectional population-based survey.
Results:
Of the 781 respondents that completed the set of questionnaires, 68% and 61% of men living with nocturia reported clinically significant (at moderate-to-severe levels) somato-vegetative and sexual AMS; the prevalence and severity were increased with advancing nighttime voiding frequency. Age, the Global PSQI score, certain metabolic diseases, the nocturia-specific QoL (NQoL) score and bedtime voiding frequency were found to be significant predictive factors for composite somato-vegetative and sexual AMS.
Conclusions:
The current findings suggested the inclusion of nocturia when measuring male-specific HRQoL related to aging.
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