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Updated: Aug 28, 2025

Evaluating Plasmonic Transport in Current-carrying Silver Nanowires
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Laser-Processed PEN with Au Nanowires Array: A Biocompatibility Assessment.

Jana Pryjmaková1, Barbora Vokatá2, Petr Slepička1

  • 1Department of Solid-State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.

International Journal of Molecular Sciences
|September 23, 2022
PubMed
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Gold nanowires show promise for biomedical uses. This study confirms gold

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Surface Engineering

Background:

  • Noble metals offer antibacterial properties but can be toxic to healthy cells.
  • Developing biocompatible antibacterial materials is crucial for medical applications.

Purpose of the Study:

  • To evaluate the biocompatibility of gold (Au) and gold/silver (Au/Ag) nanowires.
  • To validate the safety of Au nanowires for potential biomedical applications.

Main Methods:

  • Polyethylene naphthalate (PEN) modified with laser-induced periodic structures.
  • Gold (Au) deposition via vacuum evaporation.
  • Surface morphology analysis using atomic force microscopy (AFM) and scanning electron microscopy (SEM).
  • Cytotoxicity assessment using a resazurin assay on human cells.
Keywords:
biocompatibilitygold nanowireslaser-treatmentnanocompositesperiodic structures

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Main Results:

  • Surface morphology of modified PEN depended on laser incidence angle.
  • Au nanowires demonstrated safety for healthy human cells.
  • Observed cell proliferation after 72-hour incubation with Au nanowires.

Conclusions:

  • Monometallic gold nanowires are biocompatible and suitable for biomedical applications.
  • Gold enhances the biocompatibility of bimetallic Au/Ag nanowires.