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Utility of an Automated Artificial Intelligence Echocardiography Software in Risk Stratification of Hospitalized

Tom Kai Ming Wang1, Paul C Cremer1, Nicholas Chan1

  • 1Section of Cardiovascular Imaging, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Life (Basel, Switzerland)
|September 23, 2022
PubMed

Insights

Artificial intelligence (AI) software EchoGo shows promise in assessing cardiac function in COVID-19 patients. EchoGo

Area of Science:

  • Cardiology
  • Artificial Intelligence
  • Infectious Diseases

Background:

  • Cardiovascular disease is linked to poor COVID-19 outcomes.
  • AI in cardiac imaging is rapidly advancing.
  • Assessing cardiac function in COVID-19 patients is crucial for prognosis.

Purpose of the Study:

  • To evaluate the utility of AI-driven software EchoGo for analyzing echocardiograms in hospitalized COVID-19 patients.
  • To correlate EchoGo outputs with standard echocardiography measurements.
  • To assess the association of EchoGo-derived cardiac parameters with clinical outcomes.

Main Methods:

  • Fifty consecutive COVID-19 positive inpatients underwent echocardiography.
  • Echocardiograms were analyzed using EchoGo AI software.
  • EchoGo outputs were correlated with standard measurements and adjusted for APACHE-4 scores to assess clinical outcome associations.

Main Results:

  • EchoGo demonstrated strong correlations with standard echocardiography measurements for LVEDV, LVESV, LVEF, and GLS.
  • After adjusting for APACHE-4 score, EchoGo's Left Ventricular Ejection Fraction (LVEF) and Global Longitudinal Strain (GLS) were associated with adverse clinical outcomes.
  • Specifically, a 1% increase in EchoGo LVEF was associated with a decreased risk (OR 0.92), while a 1% increase in EchoGo GLS was associated with an increased risk (OR 1.22) of the primary endpoint.

Conclusions:

  • Automated AI software like EchoGo can serve as a valuable clinical tool for cardiac assessment.
  • EchoGo's LVEF and GLS measurements are associated with adverse outcomes in hospitalized COVID-19 patients.
  • EchoGo has the potential to aid in the risk stratification of COVID-19 patients with cardiac involvement.

Keywords:
COVID-19artificial intelligenceechocardiographymachine learningstrain

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