Algorithm of Femoropopliteal Endovascular Treatment
Maxime Dubosq1, Maxime Raux2, Bahaa Nasr3
1Department of Vascular and Endovascular Surgery, Institut Cœur-Poumon, 59000 Lille, France.
Insights
Choosing the right endovascular treatment for femoropopliteal lesions involves a strategic algorithm, not just device selection. Drug-eluting devices show promise for both simple and complex lesions, improving outcomes.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Endovascular treatment for femoropopliteal lesions is increasingly common.
- A growing number of devices are available, but optimal selection remains unclear.
- A structured approach is crucial for successful treatment outcomes.
Purpose of the Study:
- To outline a treatment algorithm for endovascular intervention in femoropopliteal lesions.
- To guide device selection based on lesion characteristics and procedural steps.
- To review current evidence on device efficacy.
Main Methods:
- Defining the optimal vascular access (anterograde vs. retrograde).
- Crossing lesions intraluminally or subintimally.
- Arterial preparation using angioplasty balloons, atherectomy, or intravascular lithotripsy.
- Selecting implantable devices (stents, drug-coated balloons, drug-eluting stents) based on lesion length and complexity.
Main Results:
- Retrograde approach is effective when anterograde access fails.
- Balloon angioplasty is the reference for arterial preparation, ensuring technical success and limiting complications.
- Drug-eluting devices demonstrate superior results for both simple and complex femoropopliteal lesions.
Conclusions:
- A comprehensive, algorithmic approach is essential for endovascular femoropopliteal lesion treatment.
- Device choice is a critical step within a broader treatment strategy.
- Drug-eluting devices appear to be the preferred option for optimal patient outcomes.
Abstract:
Background and Objectives: Indications for the endovascular treatment of femoropopliteal lesions have steadily increased over the past decade. Accordingly, the number of devices has also increased, but the choice of the best endovascular treatment remains to be defined. Many devices are now available for physicians. However, in order to obtain a high success rate, it is necessary to respect an algorithm whose choice of device is only one step in the treatment. Materials and Methods: The first step is, therefore, to define the approach according to the lesion to be treated. Anterograde approaches (femoral, radial, or humeral) are distinguished from retrograde approaches depending on the patient’s anatomy and surgical history. Secondarily, the lesion will be crossed intraluminally or subintimally using a catheter or an angioplasty balloon. The third step corresponds to the preparation of the artery, which is essential before the implantation of the device. It has a crucial role in reducing the rate of restenosis. Several tools are available and are chosen according to the lesion requiring treatment (stenosis, occlusion). Among them, we find the angioplasty balloon, the atherectomy probes, or intravascular lithotripsy. Finally, the last step corresponds to the choice of the device to be implanted. This is also based on the nature of the lesion, which is considered short, up to 15 cm and complex beyond that. The choice of device will be between bare stents, covered stents, drug-coated balloons, and drug-eluting stents. Currently, drug-eluting stents appear to be the treatment of choice for short lesions, and active devices seem to be the preferred treatment for more complex lesions, although there is a lack of data. Results: In case of failure to cross the lesion, the retrograde approach is a safe and effective alternative. Balloon angioplasty currently remains the reference method for the preparation of the artery, the aim of which is to ensure the intraoperative technical success of the treatment (residual stenosis < 30%), to limit the risk of dissection and, finally, to limit the occurrence of restenosis. Concerning the treatment, the drug-eluting devices seem to present the best results, whether for simple or complex lesions. Conclusions: Endovascular treatment for femoropopliteal lesions needs to be considered upstream of the intervention in order to anticipate the treatment and the choice of devices for each stage.
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