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Updated: Aug 27, 2025

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
Published on: February 27, 2019
Embelin and Its Derivatives: Design, Synthesis, and Potential Delivery Systems for Cancer Therapy
1Department of Pharmaceutical Sciences, Chicago State University, 9501 South King Drive, Chicago, IL 60628, USA.
Abstract:
Embelin is a naturally occurring benzoquinone that inhibits the growth of cancer cells, making it a potent anticancer drug. However, the low water solubility of embelin restricts its clinical applicability. This review provides a concise summary and in-depth analysis of the published literature on the design and synthesis of embelin derivatives possessing increased aqueous solubility and superior therapeutic efficacy. In addition, the potential of drug delivery systems to improve the anticancer capabilities of embelin and its derivatives is discussed.
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