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Essential Oil-Loaded Nanofibers for Pharmaceutical and Biomedical Applications: A Systematic Mini-Review.
Ioannis Partheniadis1, Georgios Stathakis1, Dimitra Tsalavouti1
1Department of Pharmaceutical Technology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Pharmaceutics
|September 23, 2022
Summary
Essential oil-loaded nanofibers (EONFs) fabricated using electrospinning show promise for pharmaceutical and biomedical applications. Further research is needed to fully understand their potential and address stability concerns.
Area of Science:
- Materials Science
- Biomedical Engineering
- Pharmacology
Background:
- Essential oils (EOs) possess antimicrobial properties utilized in food.
- Encapsulation techniques enable EO application in pharmaceuticals and biomedicine.
- Electrospinning (ES) is a versatile method for creating EO-loaded nanofibers (EONFs).
Purpose of the Study:
- To review the potential of EONFs in pharmaceutical and biomedical fields.
- To compare EONFs with traditional polymeric films.
- To provide an overview of ES technologies for EONF preparation.
Main Methods:
- Review of recent literature (2017-2022) on electrospun essential oil-loaded nanofibers.
- Analysis of conventional and coaxial electrospinning techniques.
- Evaluation of EONFs for pharmaceutical and biomedical applications.
Main Results:
- Electrospinning is effective for fabricating EONFs.
- EONFs offer advantages over traditional polymeric films for EO delivery.
- Recent research highlights the growing interest in EONFs.
Conclusions:
- EONFs show significant potential for pharmaceutical and biomedical applications.
- Gaps in literature, such as stability studies, require further investigation.
- More research is needed to fully realize the therapeutic potential of EONFs.

