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Published on: July 27, 2018
Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch)
Merly Escalona1, Jake VanCampen2, Nicholas W Maurer1
1Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Abstract:
The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
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