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Updated: Aug 27, 2025

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Vulvar melanoma: A diagnostic challenge for young women - a case report
Mouhsine Omari1,2, Adil Zaimi1,2, Hanane Hadj Kacem2,3
1Medical Oncology Department, Regional Oncology Center, Mohammed VI University Hospital, Oujda, Morocco.
Abstract:
Vulvar melanoma is a rare malignant tumor of the female genital sphere, representing postmenopausal women's prerogative, the diagnosis is based on immunohistochemicals analysis, and treatment requires a multidisciplinary approach. On account of its high metastatic potential as well as the late diagnosis given that it has non-specific clinical signs, the prognosis remains poor. In this study, we report the case of a woman of childbearing who presented a vaginal mass associated to chronic pelvic pain. Paraclinical investigations revealed a right vulvar tumoral process with pathological-looking inguinal adenomegalies on the right side with a necrotic center measuring 16.7 mm on the short axis, micronodules and secondary pulmonary nodules. The patient has been put under palliative chemotherapy, then passed out 8 months later. By this work, we attempt to review the diagnostic circumstances to better understand this delay, also to encourage self-examination and self-screening of abnormal lesions, as well as leveling the awareness of health professionals on this rare disease.
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