Related Experiment Video

Updated: Aug 27, 2025

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

11.2K

Periprosthetic knee infection after benign tumor excision complicated by carbapenem resistant Enterobacteriaceae: A

Jennifer P Adams1, Daniel Habenicht1, Duncan Ramsey2

  • 1University of Texas Rio Grande Valley School of Medicine, Harlingen, TX, USA.

Annals of Medicine and Surgery (2012)
|September 23, 2022
PubMed
Abstract

Insights

Carbapenem-resistant Enterobacteriaceae (CRE) can cause rare but serious periprosthetic joint infections (PJI) after knee surgery. Early diagnosis and a multidisciplinary approach are crucial for effective treatment of these challenging infections.

Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Microbiology

Background:

  • Periprosthetic joint infection (PJI) is a significant complication following total knee arthroscopy.
  • Enterobacter species are infrequent causes of PJI.

Observation:

  • A 65-year-old immunocompetent male developed acute right knee PJI with Carbapenem-resistant Enterobacteriaceae (CRE) two months post-operatively after intra-articular mass removal and endoprosthetic reconstruction.
  • The patient was treated with revision surgery involving a 1-stage static spacer and intravenous meropenem.

Findings:

  • CRE is an uncommon etiology for PJI, typically affecting immunocompromised individuals or those with specific risk factors.
  • This case highlights a CRE PJI in an immunocompetent host, suggesting the need for further systemic disease evaluation.

Implications:

  • This case underscores the critical need for prompt diagnosis and management of CRE joint infections.
  • A multidisciplinary strategy, incorporating aggressive surgical intervention and targeted antibiotic therapy, is essential for successful outcomes in CRE PJI.
Keywords:
Carbapenem resistant enterobacteriaceaePeriprosthetic infectionRevision arthroplastyTotal knee arthroplasty

More Related Videos

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

907
Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice18:40

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice

Published on: October 16, 2014

17.3K

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
33
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
60
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
90
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
17