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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

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Cardiovascular complications of COVID-19 severe acute respiratory syndrome

Robert J Henning1

  • 1University of South Florida 13201 Bruce B. Downs Blvd, Tampa, Florida 33612-3805, USA.

American Journal of Cardiovascular Disease
|September 23, 2022
PubMed

Insights

The Omicron variant caused record COVID-19 hospitalizations, with cardiac injury affecting over 20% of patients. Understanding these cardiac complications is crucial for reducing COVID-19 mortality.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The Omicron variant of COVID-19 has led to unprecedented hospitalizations globally.
  • Cardiac complications are frequent in hospitalized COVID-19 patients, impacting dysrhythmias, troponin levels, myocarditis, heart failure, and thromboembolic events.

Purpose of the Study:

  • To review the prevalence and mechanisms of cardiovascular injury caused by SARS-CoV-2 (the virus that causes COVID-19).
  • To outline current treatment recommendations for hospitalized COVID-19 patients with cardiac involvement.
  • To aid healthcare professionals in reducing morbidity and mortality associated with COVID-19 and post-COVID conditions.

Main Methods:

  • Literature review focusing on COVID-19 and cardiovascular complications.
  • Analysis of prevalence data for cardiac injury markers (troponin, dysrhythmias, myocarditis, heart failure, thromboembolism).
  • Synthesis of risk factors and pathophysiologic mechanisms of SARS-CoV-2 cardiovascular injury.

Main Results:

  • Cardiac injury affects at least 20% of hospitalized COVID-19 patients.
  • Specific complications include cardiac dysrhythmias (17-44%), elevated troponin (22-40%), myocarditis (2-7%), heart failure (4-21%), and thromboembolic events (15-39%).
  • Risk factors include advanced age, male sex, obesity, diabetes, pre-existing cardiovascular disease, and severe pneumonia.

Conclusions:

  • COVID-19, particularly the Omicron variant, poses significant risks to the cardiovascular system.
  • Prompt recognition and management of cardiac complications are essential for improving patient outcomes.
  • Further research into SARS-CoV-2 cardiovascular pathophysiology and treatment is warranted.

Keywords:
COVID-19 cardiac injuryanti-viral drug treatmentcytokine stormmyocardial infarctionmyocarditisstress-induced cardiomyopathyvascular thrombosis

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