Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Sutures of the Skull

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

Compact Bone

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ferroptosis in cisplatin resistance: Mechanisms and therapeutic targets.

Chinese medical journal·2026

Same author

ROS-Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Postoperative anlotinib plus radiotherapy in patients with newly diagnosed, unmethylated O<sup>6</sup>-methylguanine-DNA methyltransferase glioblastoma: A single-arm, phase 2 study.

Cancer·2026

Same author

Fasting requires Peroxiredoxin 2 and Peroxiredoxin 6 to coordinate redox dependent mitochondrial and lipid remodelling in Caenorhabditis elegans.

Redox biology·2026

Same author

Recent Progress in Mechanism-Based Therapies for <i>GJB2</i>-Related Hearing Loss.

International journal of molecular sciences·2026

Same author

Reply to Ionescu, E.C. Comment on "Chen et al. Vestibulo-Ocular Reflex Results in Patients with Intralabyrinthine Schwannomas: Case Series with a Literature Review. <i>Diagnostics</i> 2025, <i>15</i>, 2093".

Diagnostics (Basel, Switzerland)·2026

Search research articles

Related Experiment Video

Updated: Aug 27, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Diffuse-type Tenosynovial Giant Cell Tumor Invading the Temporal Bone: Three Cases.

Qilin Huang¹, Xia Wu¹, Qin Xia²

¹Department of Otorhinolaryngology, Huazhong University of Science and Technology, Wuhan, China.

Ear, Nose, & Throat Journal

|September 23, 2022

Summary

Diffuse-type tenosynovial giant cell tumor (D-TSGCT) rarely invades the temporal bone from the temporomandibular joint. This report details three rare cases, offering potential surgical insights for similar rare D-TSGCT presentations.

Keywords:

PVNS case report diffuse-type tenosynovial giant cell tumor pigmented villous nodular synovitis temporomandibular joint

More Related Videos

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

Published on: May 18, 2022

Related Experiment Videos

Last Updated: Aug 27, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

Published on: May 18, 2022

Area of Science:

Oncology
Pathology
Neurosurgery

Background:

Diffuse-type tenosynovial giant cell tumor (D-TSGCT) is a benign proliferative disease of synovial tissue.
Involvement of the temporal bone by D-TSGCT originating from the temporomandibular joint (TMJ) is exceptionally rare.

Purpose of the Study:

To report three rare cases of D-TSGCT originating from the TMJ and invading the temporal bone.
To discuss the surgical management and outcomes for these rare cases.
To provide potential surgical strategies for similar rare D-TSGCT presentations.

Main Methods:

Case series reporting three patients with D-TSGCT.
Surgical excision of the tumors.
Post-operative follow-up to assess recurrence.

Main Results:

Three cases of D-TSGCT originating from the TMJ invading the temporal bone are presented.
Tumor invasion involved the middle ear, carotid foramen, or temporal lobe in the reported cases.
Complete surgical removal was achieved in all three cases, with no recurrence observed during follow-up periods of 30, 20, and 7 months.

Conclusions:

D-TSGCT originating from the TMJ and invading the temporal bone is a rare clinical entity.
Complete surgical resection appears to be an effective treatment, leading to favorable outcomes.
This case series may offer valuable surgical insights for managing similar rare D-TSGCT cases.