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Updated: Aug 27, 2025

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
Seonaid Nolan1, Christopher Fairgrieve, Huiru Dong
1From the British Columbia Centre on Substance Use, Vancouver, BC, Canada (SN, HD); Department of Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada (SN); Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada (CF); School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada (HD); Providence Health Care, St. Paul's Hospital, Vancouver, BC, Canada (EG, HvH, BPP); Department of Family Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada (MM); Section of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Harborview Medicine Center, Seattle, WA (JIT); and Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, MA (JHS).
A hospital-based managed alcohol program (MAP) safely reduced alcohol consumption and improved liver enzymes in patients with severe alcohol use disorder. This harm reduction strategy shows promise for inpatient settings.
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