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Updated: Aug 27, 2025
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Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion
Published on: April 27, 2015
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Highlights from the Turin international workshop on liver machine perfusion
Damiano Patrono1, Nicola De Stefano1, Paulo N Martins2
1General Surgery 2U - Liver Transplant Unit, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, University of Torino, Turin, Italy.
Artificial Organs
|September 23, 2022
Summary
The 1st Turin workshop focused on liver machine perfusion (LMP) in transplantation. Experts discussed current applications, clinical uses, and future advancements in this evolving technology.
Area of Science:
- Hepatology and Transplant Surgery
- Medical Technology Innovation
Background:
- Liver transplantation is a critical treatment for end-stage liver disease.
- Machine perfusion offers a potential method to improve organ preservation and assessment.
- Standard static cold storage has limitations in evaluating organ viability.
Purpose of the Study:
- To summarize key discussions from the 1st Turin international workshop on liver machine perfusion.
- To highlight the current state of liver machine perfusion technology.
- To explore clinical indications and future directions for machine perfusion in liver transplantation.
Main Methods:
- The content is based on a summary of presentations and discussions from an international workshop.
- Key opinion leaders and delegates shared evidence, perspectives, and controversies.
- Expert consensus and reported clinical experiences formed the basis of the summary.
Main Results:
- Over 50 key opinion leaders and 220 delegates attended the workshop.
- Discussions covered the current status, clinical applications, and future potential of liver machine perfusion.
- Evidence, perspectives, and controversies regarding machine perfusion were presented and debated.
Conclusions:
- Liver machine perfusion is a rapidly developing field with significant potential in liver transplantation.
- Further research and standardization are needed to optimize clinical indications and outcomes.
- The workshop facilitated a crucial exchange of knowledge on advancing perfusion technology.
