Intraocular lens dislocation: manifestation, ocular and systemic risk factors
Jana Catharina Riedl1, Severin Rings2, Alexander K Schuster2
1Department of Ophthalmology, University Medical Center, Johannes Gutenberg-University Mainz, University Hospital Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. janac.riedl@gmail.com.
International Ophthalmology
|September 23, 2022
Summary
Posterior chamber intraocular lens (IOL) dislocation risk is higher with prior pars plana vitrectomy (PPV) and pseudoexfoliation (PEX). Combined PEX and PPV significantly increases IOL dislocation risk and shortens the time to dislocation.
Area of Science:
- Ophthalmology
- Ophthalmic Surgery
- Lens Implantation
Background:
- Posterior chamber intraocular lens (IOL) dislocation is a significant complication in ophthalmic surgery.
- Identifying risk factors is crucial for preventing IOL luxation and improving patient outcomes.
Purpose of the Study:
- To evaluate ocular and systemic risk factors associated with posterior chamber intraocular lens dislocation.
- To analyze the clinical manifestations and timing of IOL dislocation.
Main Methods:
- A retrospective case-control study was conducted between 2012 and 2016.
- Patients with IOL dislocation treated with iris-fixated IOL implantation were compared to pseudophakic controls.
- Data on previous pars plana vitrectomy (PPV) and pseudoexfoliation (PEX) were collected and analyzed.
Main Results:
- 150 eyes with IOL dislocation and 150 control eyes were analyzed.
- Previous PPV (OR=2.14) and PEX (OR=11.6) were significantly associated with increased risk of IOL dislocation.
- The time to dislocation was shorter in patients with both PEX and prior PPV compared to those with only one risk factor.
Conclusions:
- The coexistence of pseudoexfoliation (PEX) and prior pars plana vitrectomy (PPV) presents an elevated risk for intraocular lens (IOL) dislocation.
- Combined PEX and PPV lead to a significantly shorter interval between primary IOL implantation and dislocation.
- Rhegmatogenous retinal detachment was the primary indication for PPV in eyes with IOL dislocation.
Related Concept Videos
01:25Glaucoma: Overview
702
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
702
01:28Angle Closure Glaucoma: Treatment
628
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
628
01:27Open Angle Glaucoma: Treatment
527
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
527
01:17Accessory Structures of the Eye
1.7K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.7K
01:22Photoreceptors and Visual Pathways
6.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.3K