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Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

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Long-term Outcomes After Gender-Affirming Surgery: 40-Year Follow-up Study.

Rachel H Park¹, Yi-Ting Liu², Ankhita Samuel¹

¹From the Department of Plastic and Reconstructive Surgery.

Annals of Plastic Surgery

|September 23, 2022

Summary

This summary is machine-generated.

Gender-affirming surgery (GAS) offers lasting improvements in well-being for individuals with gender dysphoria. Decades later, patients report high satisfaction, reduced dysphoria, and improved mental health, with no regrets.

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Area of Science:

Medical research
Surgical outcomes
Mental health

Background:

Gender dysphoria significantly impacts patient morbidity and mortality.
Gender-affirming surgery (GAS) provides short-term well-being improvements.
Long-term durability of GAS outcomes is understudied.

Purpose of the Study:

To evaluate the long-term durability of outcomes following gender-affirming surgery.
To assess patient satisfaction and well-being decades after GAS.
To compare preoperative and postoperative measures of body congruency and mental health.

Main Methods:

Retrospective chart review of 97 patients undergoing GAS (1970-1990).
Follow-up surveys and phone interviews with 15 patients.
Comparison of preoperative and postoperative body congruency, mental health, and surgical outcomes.

Main Results:

Significant improvements in body congruency (chest, hair, voice) and reduced dysphoria.
High patient satisfaction and improved mental health, including reduced suicidal ideation.
Genital congruency scores varied, with free flap phalloplasty showing highest scores; overall long-term score was 89.6.

Conclusions:

Gender-affirming surgery is a durable treatment enhancing long-term patient well-being.
High satisfaction, reduced dysphoria, and persistent mental health benefits are observed decades post-surgery.
No patient regret was reported, underscoring the positive long-term impact of GAS.