Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

210
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
210
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

1.5K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.5K
Analgesia and Pain Management01:25

Analgesia and Pain Management

763
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
763
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

341
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
341
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

197
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
197
Narcolepsy01:07

Narcolepsy

180
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
180

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Genetic Causes of Auditory Neuropathy: A Systematic Review.

Journal of clinical medicine·2026
Same author

Superior gluteal vein entrapment: targeted surgical decompression for aberrant anatomy.

Fertility and sterility·2026
Same author

Respiratory insufficiency and sleep impairment in facioscapulohumeral muscular dystrophy.

Neuromuscular disorders : NMD·2026
Same author

Bi-allelic variants in NDUFA5 cause a mitochondriopathy with complex I deficiency.

American journal of human genetics·2026
Same author

Changes in quality of life in patients with atrial fibrillation and central sleep apnea treated with transvenous phrenic nerve stimulation.

Sleep medicine·2026
Same author

Metabolic Stroke: Atypical Presentation of Succinic Semialdehyde Dehydrogenase Deficiency.

JIMD reports·2026

Related Experiment Video

Updated: Aug 27, 2025

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

2.4K

Chronic Opioid Use and Sleep Disorders.

Shahrokh Javaheri1, Michelle Cao2

  • 1Division of Pulmonary and Sleep Medicine, Bethesda North Hospital, 10535 Montgomery Road, Suite 200, Cincinnati, OH 45242, USA; Division of Medicine, The Ohio State University, 181 Taylor Avenue, Columbus, OH 43203, USA.

Sleep Medicine Clinics
|September 23, 2022
PubMed
Summary

Opioid use surged for chronic pain management due to increased awareness and patient encouragement. A 1997 joint statement on pain treatment likely contributed to the ongoing opioid crisis.

Keywords:
Central sleep apneaDaytime sleepinessDepressionOpiates ∗ poor sleepSleep-disordered breathing

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

875
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K

Related Experiment Videos

Last Updated: Aug 27, 2025

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

2.4K
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

875
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K

Area of Science:

  • Pain Management
  • Public Health
  • Pharmacology

Background:

  • Opioid medications are integral to managing chronic pain.
  • Healthcare provider awareness and patient encouragement have driven increased opioid use over two decades.
  • A 1997 joint statement aimed to improve chronic pain treatment and awareness.

Purpose of the Study:

  • To examine the rise in opioid medication use for chronic pain.
  • To explore factors contributing to the increased prescription and use of opioids.
  • To understand the role of professional guidelines in the current opioid crisis.

Main Methods:

  • Literature review on opioid prescribing trends.
  • Analysis of factors influencing chronic pain management strategies.
  • Examination of the impact of professional society statements on opioid utilization.

Main Results:

  • Opioid utilization has significantly increased in the last 20 years.
  • Enhanced focus on chronic pain treatment and patient advocacy are key drivers.
  • The 1997 joint statement is identified as a potential contributing factor to the opioid crisis.

Conclusions:

  • The rise in opioid use is linked to increased awareness and treatment efforts for chronic pain.
  • Professional guidelines and increased patient demand have played a role in escalating opioid prescriptions.
  • Understanding these factors is crucial for addressing the opioid crisis effectively.