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Updated: Aug 27, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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Endocrine Disorders and COVID-19.

Seda Hanife Oguz1, Bulent Okan Yildiz1

  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey;

Annual Review of Medicine
|September 23, 2022
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Summary

This review explores the complex relationship between coronavirus disease 2019 (COVID-19) and endocrine disorders. It highlights how COVID-19 impacts endocrine organs and patient care, necessitating further research.

Keywords:
COVID-19SARS-CoV-2adrenalendocrine systemobesitypituitaryreproductionthyroid

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Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Public Health

Background:

  • The interaction between COVID-19 and the endocrine system is a significant research area.
  • Obesity and diabetes are known risk factors for severe COVID-19.
  • SARS-CoV-2 directly targets endocrine organs, leading to new disorders.

Purpose of the Study:

  • To review the multifaceted interactions between COVID-19 and endocrine disorders.
  • To synthesize current clinical and pathophysiological knowledge.
  • To identify future research directions.

Main Methods:

  • Literature review of clinical studies.
  • Analysis of pathophysiological mechanisms.
  • Synthesis of existing scientific knowledge.

Main Results:

  • COVID-19 affects endocrine function and organs.
  • Pre-existing endocrine conditions increase COVID-19 severity.
  • Pandemic measures disrupted care for endocrine patients.
  • New-onset endocrine disorders linked to COVID-19 observed.

Conclusions:

  • COVID-19 has significant implications for endocrine health.
  • Further research is crucial to understand long-term effects and optimize patient care.
  • The pandemic highlighted vulnerabilities in managing endocrine disorders.