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Updated: Aug 27, 2025
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Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells
Maria Grazia Cascio1, Pietro Marini1, Roger G Pertwee2
1School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Abstract:
Displacement binding assays are nonfunctional assays mostly used with the aim of determining whether a certain compound (plant-derived or synthetic) can bind to a specific receptor with high affinity. Here, we describe the displacement binding assay that is carried out with a radioligand and CHO (Chinese Hamster Ovarian) cells stably transfected with the human cannabinoid CB2 receptor.
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