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Bowel ischaemia in COVID-19 infection: a scoping review protocol
Yi Zhao1, Jhia Jiat Teh2,3, Victor Kung4
1Imperial College London, London, UK yi.zhao18@imperial.ac.uk.
Insights
This review examines COVID-19's link to gastrointestinal ischemia, a serious non-pulmonary complication. It synthesizes current evidence to increase awareness among healthcare professionals about this critical condition.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Vascular Medicine
Background:
- COVID-19 (Coronavirus Disease 2019) presents with diverse clinical manifestations affecting multiple organ systems.
- While thromboembolism is a known risk, gastrointestinal ischemia is an emerging, serious complication.
- Awareness of COVID-19-associated gastrointestinal ischemia is crucial for healthcare professionals.
Purpose of the Study:
- To conduct a scoping review of existing literature on COVID-19-related gastrointestinal ischemia.
- To collate and synthesize current evidence on this non-pulmonary complication.
- To raise awareness among healthcare providers regarding this significant association.
Main Methods:
- Adherence to the Arksey and O'Malley methodological framework (2005) and Joanna Briggs Institute methodology for scoping reviews.
- Systematic literature search across databases including EMBASE, PubMed, and MEDLINE.
- Independent screening of titles, abstracts, and full-text articles by two reviewers, followed by data extraction.
Main Results:
- The review will present findings in a tabular format, accompanied by a narrative discussion.
- It will provide a comprehensive overview of the association between COVID-19 infection and bowel ischemia.
- Ethical and methodological challenges will be discussed to inform future research.
Conclusions:
- This scoping review will highlight the association between COVID-19 and gastrointestinal ischemia.
- It aims to establish a foundation for a future research agenda on this topic.
- Findings will be disseminated through peer-reviewed publications and conference presentations.
Introduction:
COVID-19 disease was declared as a pandemic by WHO since March 2020 and can have a myriad of clinical presentations affecting various organ systems. Patients with COVID-19 are known to have an increased risk of thromboembolism, including cardiovascular, pulmonary and cerebral ischaemic events. However, an increasing number of case studies have reported that COVID-19 infection is also associated with gastrointestinal ischaemia. This scoping review aims to collate the current evidence of COVID-19-related gastrointestinal ischaemia and raise awareness among healthcare professionals of this lesser known, but serious, non-pulmonary complication of COVID-19 infection.
Methods:
The proposed scoping review will be conducted as per the Arksey and O'Malley methodological framework (2005) the Joanna Briggs Institute methodology for scoping reviews. A systematic search will be undertaken on different databases including EMBASE, PubMed and MEDLINE. Two independent reviewers will screen titles, abstracts and full-text articles according to the inclusion criteria and extract relevant data from the included articles. Results will be presented in a tabular form with a narrative discussion.
Ethics And Dissemination:
Ethical approval will not be required for this scoping review. This scoping review will provide an extensive overview of the association between COVID-19 infection and bowel ischaemia. Further ethical and methodological challenges will also be discussed in our findings to define a new research agenda. Findings will be disseminated through peer-reviewed publications and presentations at both national and international conferences.
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