The impact of birth weight and gestational age on acute mastoiditis in children

Elchanan Zloczower1, Noam Bartov2, Raviv Allon2

  • 1Department of Otolaryngology-Head and Neck Surgery, Kaplan Medical Center, Hadassah Medical School, The Hebrew University of Jerusalem, Rehovot, Israel. chanani9@gmail.com.

Insights

Low birth weight (LBW) and preterm birth do not increase acute mastoiditis (AM) severity or complications. However, LBW infants develop AM later, and preterm infants experience recurrent AM more frequently.

Area of Science:

  • Pediatrics
  • Otolaryngology
  • Neonatology

Background:

  • Previous studies link preterm birth and low birth weight (LBW) to acute otitis media.
  • The relationship between LBW/preterm birth and acute mastoiditis (AM) requires further investigation.

Purpose of the Study:

  • To examine the impact of LBW and preterm birth on AM severity.
  • To assess neuro-otological complications and recurrence rates in infants with AM.
  • To identify distinct disease courses in LBW and preterm infants with AM.

Main Methods:

  • Retrospective cohort study of 294 children diagnosed with AM between 1999 and 2020.
  • Data collected included gestational age, birth weight, clinical presentation, laboratory results, imaging, and long-term outcomes.
  • Comparison between LBW/preterm infants and normal birth weight/gestational age infants.

Main Results:

  • No significant differences in AM severity, laboratory findings, imaging, or late complications were observed between LBW and normal birth weight (NBW) groups, or between preterm and normal gestational age groups.
  • LBW children were diagnosed with AM at a statistically older age (2.28 years) compared to NBW children (1.84 years).
  • Preterm infants showed a higher propensity for recurrent AM episodes with shorter intervals between events.

Conclusions:

  • LBW and preterm birth are not independent risk factors for increased AM severity, intervention needs, or future complications.
  • LBW infants present with AM at an older age, and preterm infants are more susceptible to recurrent AM, indicating unique disease trajectories.
Abstract

Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.4K
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
162
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.2K
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
423
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
33
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
485