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Updated: Aug 27, 2025

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
[Current Management of Congenital Diaphragmatic Hernia]
Megumi Nakamura1, Motoshi Wada
1Department of Surgery, Miyagi Children's Hospital, Sendai, Japan.
Abstract:
Bochdalek hernia is the most common type of congenital diaphragmatic hernia( CDH). Patients with CDH often develop cardiopulmonary dysfunction secondary to pulmonary hypoplasia and pulmonary hypertension, which necessitates emergency surgery. Advanced cardiopulmonary management is essential in such cases;therefore, patients should be treated at a well-facility that is familiar with the treatment of CDH. Respiratory management using gentle ventilation and control of pulmonary hypertension using nitric oxide are necessary for preoperative stabilization of patients. Intraoperatively, the hernia should be cautiously reduced and contents should be returned into the abdominal cavity. Surgery is performed to secure the circumference of the rim and ensure firm closure of the defect. Thoracoscopic surgery may be considered for late-onset cases with a stable general condition.
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