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Type 2 autoimmune pancreatitis associated with severe ulcerative colitis: Three case reports.
Mark Ghali1,2, Karen Bensted1, David B Williams1,3
1Department of Gastroenterology, St Vincent's Hospital, Darlinghurst 2010, NSW, Australia.
World Journal of Clinical Cases
|September 26, 2022
Summary
Type two autoimmune pancreatitis, a rare steroid-responsive condition, can occur with inflammatory bowel disease. Early diagnosis is crucial to avoid unnecessary pancreatic surgery.
Area of Science:
- Gastroenterology
- Immunology
Background:
- Type two autoimmune pancreatitis is a rare, steroid-responsive pancreatic condition.
- It is a non-IgG4 inflammatory pancreatopathy.
- It can be associated with inflammatory bowel disease.
Observation:
- This case series presents three patients with autoimmune pancreatitis.
- These patients had varied clinical presentations and re-presentations.
- All cases were associated with an aggressive course of ulcerative colitis.
Findings:
- Autoimmune pancreatitis occurred independently of bowel disease activity.
- In one patient, pancreatitis developed after colectomy.
Implications:
- Increased clinician awareness is vital for early diagnosis and treatment.
- Prompt diagnosis can prevent unnecessary pancreatic surgery.
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