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Unilateral lichen planus with Blaschko line distribution: A case report
Shuai Dong1, Wen-Jing Zhu1, Meng Xu1
1Department of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
World Journal of Clinical Cases
|September 26, 2022
Summary
Lichen planus along Blaschko's lines is rare, especially with unilateral lesions and nail involvement. This case highlights a unique presentation and successful treatment of this uncommon dermatological condition.
Area of Science:
- Dermatology
- Genodermatoses
Background:
- Lichen planus (LP) along Blaschko's lines is a rare dermatological condition, affecting 0.24%-0.62% of patients.
- Unilateral distribution of LP lesions on the limbs and trunk is uncommon.
- Nail lesions occur in approximately 10% of LP patients.
Observation:
- A 20-year-old woman presented with a 5-month history of polygonal, purpuric papules on the right arm, leg, and trunk.
- The patient developed nail deformation followed by a pruritic, maculopapular rash, with lesions distributed unilaterally along Blaschko's lines.
- Dermoscopy and skin biopsy confirmed the diagnosis of LP along Blaschko's lines.
Findings:
- The patient's cutaneous lesions significantly improved after a 4-week treatment regimen.
- Treatment included intramuscular and topical glucocorticoids, oral acitretin, and topical retinoids.
- This case demonstrates a rare presentation of LP involving multiple body segments along Blaschko's lines with concurrent nail damage.
Implications:
- This case underscores the rarity of LP presenting along Blaschko's lines with extensive unilateral skin and nail involvement.
- Effective management strategies involve a combination of systemic and topical therapies.
- Further research into the pathogenesis and treatment of Blaschko's linear LP is warranted.
