From E. coli UTI to Spots on the Thigh: A Rare Cause of Erythema Multiforme

Erythema multiforme has largely been associated with microbes such as herpes simplex virus and Mycoplasma pneumoniae, drugs, and autoimmune conditions. Here, we report an unusual presentation of erythema multiforme secondary to Escherichia coli (E. coli) UTI in a pediatric patient. A literature search was conducted and a similar case describing the association between erythema multiforme and hematuria secondary to an E. coli UTI in an adult male was identified. However, no case describing E. coli manifesting in erythema multiforme has been described in the pediatric patient population previously.