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Updated: Aug 27, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Perspective: repurposed drugs for COVID-19
Kesara Na-Bangchang1, Supatra Porasuphatana2, Juntra Karbwang1
1Drug Discovery and Development Center, Office of Advanced Science and Technology, Thammasat University, Pathumthani, Thailand.
Introduction:
The article aims to emphasize the necessity of proper research design, both scientifically and ethically, in order to provide good evidence for physicians to base their decisions on when prescribing drug treatment.
Methods:
Research articles and guidelines related to therapy of COVID-19 were searched from the PubMed database.
Results:
Only remdesivir and tocilizumab are medicines that have been approved by the US FDA's decision to approve their clinical use in moderate and severe COVID-19.
Conclusions:
Favipiravir, ivermectin and andrographolide need further well-conducted research to confirm the efficacy and safety against COVID-19 at different stages.
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