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Updated: Aug 27, 2025

Author Spotlight: Decoding Corneal Neovascularization with Alkali Burn Model for Future Therapeutic Strategies
Published on: June 30, 2023
Expanding the Spectrum of Alkali Retinopathy: Maculopathy following Alkali Burn
Andreas Vanclooster1, Julie De Zaeytijd1, Dimitri Roels1
1Department of Ophthalmology, Ghent University Hospital, Ghent, Belgium.
Abstract:
Ocular alkali burns are known to cause profound damage to the anterior segment, especially the cornea and conjunctiva. However, rarely, additional adjacent chorioretinal complications may ensue. These chorioretinal complications appear primary by direct penetration of the alkali or secondary to an elevated intraocular pressure (IOP). In contrast to this, recent animal studies have suggested a causal link with upregulation of proinflammatory mediators. We present a patient with maculopathy following alkali ocular burn.
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