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Surgical drainage procedures for paediatric chronic pancreatitis: a scoping review
Tristan Boam1, Melissa Gabriel2, Bethan G Rogoyski3
1Department of Paediatric Surgery, Queens Medical Centre, Nottingham University Hospitals Trust, Derby Road, Nottingham, NG7 2UH, UK. tristanboam@doctors.org.uk.
Insights
Paediatric chronic pancreatitis (CP) surgery outcomes are generally favorable but lack robust evidence. Centralization and registries are recommended for better long-term follow-up in children.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Pancreatic Diseases
Background:
- Pediatric chronic pancreatitis (CP) is rare but causes severe complications like pseudocysts and pain.
- Surgical interventions are sometimes necessary but lack evidence on efficacy and long-term outcomes in children.
Purpose of the Study:
- To conduct a scoping review of contemporary studies on surgical pancreatic drainage procedures in children (<18 years).
- To assess the current evidence regarding surgical management of pediatric CP.
Main Methods:
- A scoping review of studies published post-2000 was performed.
- Included 24 case series involving 248 pediatric patients undergoing surgical pancreatic drainage.
Main Results:
- Longitudinal pancreaticojejunostomy and cystogastrostomy were common procedures for CP and pseudocysts, respectively.
- Generally favorable outcomes were reported, but all studies had a high risk of bias.
- Evidence is limited to Level IV case series due to the rarity of the condition.
Conclusions:
- Surgical management for pediatric CP is infrequent, making large prospective studies challenging.
- Centralization of care and establishment of patient registries are recommended to improve data quality and long-term follow-up.
Abstract:
Paediatric chronic pancreatitis (CP) is a relatively rare entity, but it can be accompanied by debilitating complications such as pseudocysts, chronic pain and pancreatic duct obstruction. Surgical drainage procedures, such as pancreaticojejunostomy or cystogastrostomy/jejunostomy to address these complications may be required; however, there is a paucity of evidence as to the efficacy and long-term outcomes of these operations in the paediatric population. A scoping review of contemporary (post-2000) studies detailing surgical pancreatic drainage procedures performed in children (< 18 years) was undertaken. After screening, 24 case series detailing a total of 248 patients met the inclusion criteria. Longitudinal pancreaticojejunostomy and cystogastrostomy were the most common surgical procedures performed in children with CP and pseudocysts, respectively. Overall generally favourable outcomes were reported, but all studies were considered to have a high risk of bias. Operative management for paediatric CP is infrequently required; therefore, large prospective studies or trials focusing on this population are infeasible, limiting the best available evidence on the topic to case series, level IV. Recommendations to improve the quality of surgical care in the paediatric CP population could include centralisation and the formation of registries to allow accurate long-term follow-up.
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