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Updated: Aug 27, 2025

The Supraclavicular Fossa Ultrasound View for Central Venous Catheter Placement and Catheter Change Over Guidewire
Published on: December 23, 2014
Should ultrasound evaluation for catheter-related thrombosis always be required before PICC removal?
Fulvio Pinelli1, Mirko Muzzi2, Mauro Pittiruti3
1AOUC, Anesthesia and Intensive Care, Florence, Tuscany, Italy.
Insights
Peripherally inserted central catheters (PICCs) can cause asymptomatic thrombosis, posing a rare risk of pulmonary embolism upon removal. Ultrasound screening before PICC removal is debated due to cost and logistics.
Area of Science:
- Vascular Medicine
- Interventional Radiology
- Critical Care Medicine
Background:
- Catheter-related thrombosis (CRT) is a known complication of central venous catheters, including peripherally inserted central catheters (PICCs).
- While often asymptomatic, CRT carries a theoretical risk of thrombus mobilization and subsequent pulmonary embolism upon catheter removal.
- Current guidelines lack clear recommendations on routine ultrasound screening for asymptomatic CRT before PICC removal.
Discussion:
- The clinical utility of routine ultrasound screening for asymptomatic CRT before PICC removal is debated.
- Screening offers potential patient safety benefits by identifying thrombi that could cause embolism.
- However, widespread adoption faces logistical challenges and significant costs, potentially outweighing benefits for asymptomatic cases.
Key Insights:
- Asymptomatic CRT is common with PICCs and other central venous catheters.
- The risk of pulmonary embolism from removing a PICC with an asymptomatic thrombus is theoretically possible but likely low.
- The cost-effectiveness and logistical feasibility of routine ultrasound screening remain significant barriers.
Outlook:
- Further research is needed to establish evidence-based guidelines for managing asymptomatic CRT in PICC patients.
- Developing cost-effective screening methods or risk stratification tools could aid clinical decision-making.
- Future recommendations may focus on selective screening based on patient risk factors rather than universal application.
Abstract:
Despite several effective preventive strategies peripherally inserted central catheters (PICCs)-as much as centrally inserted central catheters and femorally inserted central catheters-are inevitably associated with the potential development of catheter-related thrombosis. This complication may be symptomatic or-more often-asymptomatic. Even if remote, the chance that PICC removal may mobilize an asymptomatic thrombus and cause pulmonary embolism, is theoretically possible. On the other hand, the diffuse adoption of an ultrasound scan aiming at detecting an asymptomatic catheter-related thrombosis may be logistically difficult and expensive. No clear evidence-based recommendations exist on this issue and whether perform an ultrasound scan before PICC removal in asymptomatic patients remains a matter of debate. For these reasons, the authors propose few common sense recommendations that may help clinicians in weighing the clinical advantages of the exam (optimal safety for the patient) versus its practical disadvantages (logistic cost).
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