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Published on: May 24, 2024
Systematic review of exercise therapy in the management of post-thrombotic syndrome
Sara Jasionowska1,2, Benedict R H Turner1,2, Matthew Machin1,2
1Section of Vascular Surgery, Department of Surgery and Cancer, 170714Imperial College London, London, UK.
Objectives:
Exercise improves haemodynamic parameters in patients with chronic venous disease. There is a paucity of evidence on its effect in post-thrombotic syndrome (PTS). The aim of this systematic review is to assess the impact of exercise in PTS.
Methods:
Adhering to PRISMA guidelines and following PROSPERO registration (CRD42021220924), MEDLINE, Cochrane Library, EMBASE database, and trial registries were searched on 19th May 2022.
Results:
One article met the inclusion criteria and a narrative synthesis was carried out. The included randomised controlled trial reported a between-group mean difference of 4.6 points (p = .027) in the VEINES-QOL score and -2.0 points (p = .14) in the Villalta score, in favour of exercise therapy. The statistical significance threshold was not reached.
Conclusion:
Data on exercise in PTS remains sparse but exercise appears to be a safe intervention. In the context of this literature, a potential future trial and outcome reporting measures are suggested.
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