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Hypercalcaemia caused by calcium sulfate beads.

Samuel Epstein¹, Diego E Vanegas Acosta²

¹College of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.

BMJ Case Reports

|September 27, 2022

Summary

Acute hypercalcaemia can arise from calcium sulfate antibiotic beads used in orthopaedic surgery. Careful review of patient records, including medical products, is crucial for diagnosing unexplained metabolic disturbances.

Keywords:

Calcium and bone Hip implants Medical management Metabolic disorders

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A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

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Area of Science:

Metabolic disturbances
Calcium regulation
Orthopaedic surgery

Background:

Hypercalcaemia is a common hospital finding.
Calcium regulation involves complex systems, making diagnosis challenging.
Antibiotic beads are used in orthopaedic procedures for bone void filling and local antibiotic delivery.

Observation:

A patient developed acute hypercalcaemia.
The hypercalcaemia was linked to calcium sulfate-containing antibiotic beads used during an orthopaedic procedure.

Findings:

Calcium sulfate-containing antibiotic beads can cause acute hypercalcaemia.
Thorough review of a patient's medical history, including undocumented medical products, is essential.

Implications:

Highlights a potential iatrogenic cause of hypercalcaemia.
Emphasizes the need for comprehensive patient record review in diagnosing metabolic abnormalities.
Suggests improved documentation practices for medical implants and products.