Related Experiment Video

Updated: Aug 27, 2025

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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Left Main Coronary Artery Disease: The Forgotten Lead of Electrocardiogram Is Predictive

Pradnya Brijmohan Bhattad1, Akil A Sherif1, Ajay K Mishra1

  • 1Cardiovascular Medicine, Saint Vincent Hospital, University of Massachusetts (UMass) Chan Medical School, Worcester, USA.

Cureus
|September 28, 2022
PubMed

Insights

ST segment elevation in lead aVR with diffuse ST depression during chest pain indicates severe coronary artery disease, such as left main or multi-vessel disease, requiring urgent angiogram.

Area of Science:

  • Cardiology
  • Diagnostic Electrocardiography
  • Interventional Cardiology

Background:

  • ST segment elevation in lead aVR, particularly with diffuse ST depression, is an uncommon but critical electrocardiographic finding.
  • This pattern suggests significant left ventricular strain and is associated with severe coronary artery disease.

Keywords:
avr leadecgleft main coronary artery disease (lmcad)proximal left anterior descending artery diseasesubendocardial ischemia

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