Uterine adenomyotic cyst with markedly elevated serum CA19‑9 and CA125 levels: A case report

Adenomyotic cysts are small cysts with a diameter of <5 mm, usually containing hemorrhagic material. The present study reported on a patient with a large adenomyotic cyst with abnormally high serum levels of CA19-9 (>1,000 U/ml) and CA125 (642 U/ml) and a complaint of pelvic pain. MRI scans were critical in diagnosing the case. Adhering to the principle of tumor-free implantation, a laparotomy was performed. After the operation, six weeks were required to normalize the serum level of CA19-9 and four weeks for CA125. Elevated tumor markers are frequently observed in malignancies, but the outcome reported in the present case was a benign lesion and the prognosis was favorable. In the present case, it was unusual that CA19-9 was elevated in addition to CA125, as it is commonly reported that only CA125 is elevated in cases of large adenomyotic cyst.