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Related Concept Videos

Lift01:23

Lift

220
Lift is a fundamental aerodynamic force that acts perpendicular to the direction of airflow. It plays a central role in achieving and sustaining flight and in stabilizing various vehicles. Lift primarily originates from pressure differences created across surfaces, such as an airfoil. A lower pressure region forms above the wing, while a higher pressure region forms below it, generating an upward force. This differential results from the shape and orientation of the airfoil, enabling the wing...
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General External Flow Characteristics01:26

General External Flow Characteristics

258
The study of external flow is essential for creating structures and objects that interact efficiently and safely with moving fluids, such as air or water. When a body is immersed in a flowing fluid, it experiences two primary forces: drag, which opposes motion along the flow direction, and lift, which acts perpendicular to the flow. The shape, size, and orientation of the object influence these forces.Streamlined and Blunt Bodies in External FlowObjects in fluid flow are classified as...
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Free Jet01:14

Free Jet

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Free jets describe the flow of liquid exiting a reservoir through an opening into the atmosphere without resistance. The velocity (v) of the liquid jet is derived using Bernoulli's principle and expressed as:
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Flail Chest-II01:26

Flail Chest-II

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Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
226

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Related Experiment Video

Updated: Aug 27, 2025

Engineered Vascularized Muscle Flap
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Techniques and Innovations in Flap Engineering: A Review.

Elizaveta Kouniavski1,2, Dana Egozi1,2, Yoram Wolf3,4

  • 1Kaplan Medical Center, Department of Plastic and Reconstructive Surgery, Rehovot, Israel.

Plastic and Reconstructive Surgery. Global Open
|September 28, 2022
PubMed
Summary

Tissue engineering offers innovative solutions for complex defect reconstruction, aiming to reduce donor site morbidity associated with traditional autologous tissue flaps. This field explores novel flap engineering techniques for improved patient outcomes.

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Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Plastic Surgery

Background:

  • Autologous tissue flaps, including vascularized composite allografts, are the current standard for complex defect reconstruction.
  • Despite good clinical results, traditional methods face challenges like limited donor sites, donor site morbidity, and complex surgical procedures.
  • Tissue engineering research focuses on developing novel flaps with minimal or no donor site sacrifice, leveraging tissue regeneration and neovascularization.

Purpose of the Study:

  • To review contemporary technologies in flap engineering for complex defect reconstruction.
  • To identify promising tissue engineering strategies that address limitations of current reconstructive methods.

Main Methods:

  • A comprehensive literature review was conducted using PubMed.
  • Search terms focused on flap engineering within the field of plastic surgery.
  • Relevant published articles were identified and analyzed.

Main Results:

  • The review surveys advanced flap engineering technologies, including cell sheet technology, prefabricated flaps, and tissue engineering chambers.
  • These innovative approaches hold potential for regenerating tissues and promoting neovascularization.
  • Some techniques are progressing towards large animal models and human studies.

Conclusions:

  • Tissue engineering presents a promising avenue for managing large and complex tissue defects.
  • Emerging flap engineering technologies offer potential solutions to overcome the limitations of current reconstructive surgery.
  • Further research and clinical trials are warranted to translate these advancements into widespread clinical practice.