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Updated: Aug 27, 2025

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
[Advances in heart failure treatment: a summary of 50 years of evolution]
Marco Metra1, Giuliana Cimino1, Elisa Pezzola1
1U.O.C. Cardiologia, ASST Spedali Civili, Dipartimento di Specialità Medico-Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Università degli Studi, Brescia.
Abstract:
Management of heart failure is one of the most important challenges of modern medicine. Heart failure affects a large number of patients worldwide and its prevalence is increasing. The adoption of the methodology of randomized controlled trials has led to the identification of drugs and devices that prolong life and, in many cases, also yield a better quality of life. Improvement in the diagnostic techniques and devices has also led to better treatment of most major comorbidities, another strong driver of patient's symptoms and natural history. This article aims to provide an overview of the key events that have led to such improvement.
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