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Cardiovascular Health and Atrial Fibrillation or Flutter: A Cross-Sectional Study from ELSA-Brasil

Itamar S Santos1,2, Paulo A Lotufo1,2, Alessandra C Goulart2

  • 1Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo , São Paulo , SP - Brasil.

Arquivos Brasileiros De Cardiologia
|September 28, 2022
PubMed

Insights

Ideal cardiovascular health (ICVH) scores did not predict atrial fibrillation or flutter (AFF). However, ideal blood pressure and total cholesterol levels showed significant associations with AFF diagnosis, suggesting individual metrics are more informative than overall scores for AFF prevention.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • The relationship between ideal cardiovascular health (ICVH) and atrial fibrillation or flutter (AFF) remains underexplored compared to other cardiovascular conditions.
  • Understanding this association is crucial for developing targeted prevention strategies.

Purpose of the Study:

  • To investigate the association between atrial fibrillation or flutter (AFF) diagnosis and ideal cardiovascular health (ICVH) metrics and composite scores.
  • The study utilized data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Main Methods:

  • Analysis included 13,141 participants with complete data.
  • ICVH metrics (diet, physical activity, BMI, smoking, blood pressure, glucose, cholesterol) and scores were assessed using American Heart Association criteria.
  • Binary logistic regression models were employed to determine associations, with significance set at p < 0.05.

Main Results:

  • In adjusted models, overall ICVH scores were not significantly linked to prevalent AFF (OR: 0.96; 95% CI: 0.80-1.16).
  • Ideal blood pressure (OR: 0.33; 95% CI: 0.15-0.74) and total cholesterol (OR: 1.88; 95% CI: 1.19-2.98) profiles demonstrated significant associations with AFF diagnosis.

Conclusions:

  • Global ICVH scores did not show a significant association with AFF diagnosis after multivariable adjustment.
  • Antagonistic associations between AFF and specific ICVH metrics (blood pressure, cholesterol) suggest that individual metrics, rather than composite scores, may be more relevant for AFF prevention strategies.
Abstract

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