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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Imaging Studies III: Computed Tomography01:27

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Related Experiment Video

Updated: Aug 27, 2025

Murine Fetal Echocardiography
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Microfocus computed tomography for fetal postmortem imaging: an overview.

Daniël Docter1, Yousif Dawood1,2,3, Karl Jacobs1,3,4

  • 1Department of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.

Pediatric Radiology
|September 28, 2022
PubMed
Summary
This summary is machine-generated.

Fetal postmortem microfocus computed tomography (micro-CT) offers a less invasive alternative to traditional autopsy, especially for early-gestation fetuses. Contrast-enhanced micro-CT shows promise as a diagnostic tool, potentially replacing autopsy in certain cases.

Keywords:
AnatomyAutopsyDiffusible iodine-based contrast-enhanced computed tomographyFetusHumanIntrauterine fetal demiseMicrofocus computed tomographyPostmortemStillbirth

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Area of Science:

  • Medical Imaging
  • Radiology
  • Fetal Pathology

Background:

  • Fetal postmortem microfocus computed tomography (micro-CT) is gaining traction for diagnostics and research.
  • Micro-CT may replace autopsy in early gestation fetuses, where autopsy is challenging and often refused.
  • This imaging modality offers a less invasive approach to fetal examination.

Purpose of the Study:

  • To review the latest research in fetal postmortem micro-CT imaging.
  • To focus on diagnostic accuracy, endovascular staining techniques, and placental imaging.
  • To explore potential applications for larger fetuses and rare specimens.

Main Methods:

  • Review of current literature on fetal postmortem micro-CT.
  • Analysis of diagnostic accuracy studies.
  • Evaluation of endovascular staining methods and placental imaging techniques.
  • Discussion of emerging techniques for larger fetuses.

Main Results:

  • Contrast-enhanced micro-CT demonstrates potential as a viable alternative to fetal autopsy.
  • Endovascular staining approaches are key for detailed imaging.
  • Placental studies using micro-CT are advancing.
  • Reversibility of staining and methods for larger fetuses are under investigation.

Conclusions:

  • Contrast-enhanced micro-CT is a promising non-invasive alternative to fetal autopsy.
  • Further research is needed to fully establish its role and expand applications.
  • Micro-CT may have future uses in imaging rare specimens and advancing fetal diagnostics.