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Updated: Aug 27, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Half a century of bioethics and philosophy of medicine: A topic-modeling study
Piotr Bystranowski1, Vilius Dranseika1, Tomasz Żuradzki1
1Interdisciplinary Centre for Ethics & Institute of Philosophy, Jagiellonian University in Kraków, 31-044, Kraków, Poland.
Abstract:
Topic modeling-a text-mining technique often used to uncover thematic structures in large collections of texts-has been increasingly frequently used in the context of the analysis of scholarly output. In this study, we construct a corpus of 19,488 texts published since 1971 in seven leading journals in the field of bioethics and philosophy of medicine, and we use a machine learning algorithm to identify almost 100 topics representing distinct themes of interest in the field. On the basis of intertopic correlations, we group the content-based topics into eight clusters, thus providing a novel, fine-grained intellectual map of bioethics and philosophy of medicine. Moreover, we conduct a number of diachronic analyses, examining how the "prominence" of different topics has changed across time. In this way, we are able to observe the distinct patterns in which bioethics and philosophy of medicine have evolved and changed their focus over the past half a century.
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