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ICTV Virus Taxonomy Profile: Hepeviridae 2022
Michael A Purdy1, Jan Felix Drexler2, Xiang-Jin Meng3
1Centers for Disease Control and Prevention, Atlanta, GA, USA.
The Journal of General Virology
|September 28, 2022
Summary
The Hepeviridae family comprises viruses causing hepatitis in mammals, birds, and fish. This report summarizes the International Committee on Taxonomy of Viruses findings on this viral family.
Area of Science:
- Virology
- Taxonomy
- Public Health
Background:
- The family Hepeviridae encompasses RNA viruses with diverse hosts, including mammals, birds, and fish.
- Hepatitis E virus (HEV) causes acute hepatitis in humans, potentially leading to chronic infection and extrahepatic issues in immunocompromised individuals.
- Avian hepatitis E virus is linked to hepatitis-splenomegaly syndrome in chickens.
Purpose of the Study:
- To provide a summary of the International Committee on Taxonomy of Viruses (ICTV) report on the family Hepeviridae.
- To outline the classification and characteristics of viruses within the Hepeviridae family.
- To present the current taxonomic status of Hepeviridae, including genera Orthohepevirinae and Parahepevirinae.
Main Methods:
- Review and summarization of the official ICTV report.
- Analysis of viral classification and nomenclature.
- Compilation of key characteristics for Hepeviridae genera and subfamilies.
Main Results:
- The Hepeviridae family is divided into two subfamilies: Orthohepevirinae (mammals and birds) and Parahepevirinae (fish).
- Key genera include Paslahepevirus (e.g., human HEV) and Avihepevirus (avian HEV).
- The report details the taxonomic structure and relationships within the family.
Conclusions:
- The ICTV report provides a standardized classification for the Hepeviridae family.
- Understanding Hepeviridae taxonomy is crucial for research into viral pathogenesis, transmission, and control.
- This summary facilitates access to the official classification of these important viruses.
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