Related Experiment Video
Updated: Aug 27, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
Losing the battle over best-science guidance early in a crisis: COVID-19 and beyond
Lucia Illari1, Nicholas J Restrepo2, Neil F Johnson1
1Physics Department, George Washington University, Washington, D.C. 20052, USA.
Abstract:
Ensuring widespread public exposure to best-science guidance is crucial in any crisis, e.g., coronavirus disease 2019 (COVID-19), monkeypox, abortion misinformation, climate change, and beyond. We show how this battle got lost on Facebook very early during the COVID-19 pandemic and why the mainstream majority, including many parenting communities, had already moved closer to more extreme communities by the time vaccines arrived. Hidden heterogeneities in terms of who was talking and listening to whom explain why Facebook's own promotion of best-science guidance also appears to have missed key audience segments. A simple mathematical model reproduces the exposure dynamics at the system level. Our findings could be used to tailor guidance at scale while accounting for individual diversity and to help predict tipping point behavior and system-level responses to interventions in future crises.
Related Concept Videos
Steps in Outbreak Investigation
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Principles of Disease Surveillance
Acute Coronary Syndrome IV: Interprofessional Care
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

