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Updated: Aug 27, 2025

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
Geriatric Pharmacotherapy Case Series: Poly-Provider Leading to Polypharmacy
Megan E Matthews1, Patricia Evangelista1, Tatyana Gurvich1
1University of Southern California, Los Angeles, California.
Abstract:
Background: This case study reviews the complicated treatment of an older person under the care of numerous specialists in the ambulatory care setting. As various providers made concurrent changes in pharmacotherapy without communication with other providers, the patient experienced acute changes and decompensation. Assessment: Polypharmacy played a significant role in the acute decompensation of the patient. Changes made in the context of specific specialties inadvertently had a negative impact on other disease states. Outcome: Intentional communication between all providers on the patient's health care team resulted in a deeper understanding of the overall plan and therapeutic goals. Care synchronization ultimately improved patient outcomes. The clinical pharmacy team provided multiple pharmacotherapy recommendations to improve pain and anxiety without jeopardizing safety and therapeutics for other disease states. These interventions provided a key element that streamlined and improved patient-centered care. Conclusion: In this case, poly-provider was responsible for polypharmacy that significantly impacted the patient's care and quality of life. Pharmacists and the pharmacists' patient care process play a significant role in improving patient-centered care by identifying medication changes and potential side effects, especially in the wake of interventions by multiple providers.
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