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The sickle cell gene is widespread in India
Summary
The sickle cell gene is widespread in India, not just in tribal groups. This study found it is common across Hindu society, particularly in upper and scheduled castes.
Area of Science:
- Genetics
- Population Health
Background:
- The sickle cell gene was initially identified in South Indian tribal populations.
- This led to a misconception that its prevalence was limited to these groups.
Purpose of the Study:
- To investigate the prevalence and distribution of the sickle cell gene in Orissa, India.
- To determine if the gene is confined to tribal groups or widespread in the general population.
Main Methods:
- The study involved population-based screening for the sickle cell gene.
- Data was collected across various social strata within the state of Orissa.
Main Results:
- The sickle cell gene is prevalent throughout Orissa, extending beyond tribal communities.
- Its occurrence is higher in upper and scheduled castes compared to tribal groups.
Conclusions:
- The sickle cell gene is widely distributed across diverse social groups in Orissa.
- Previous assumptions about its limited presence in tribal populations are inaccurate.