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Updated: Aug 27, 2025

Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy
Published on: July 9, 2016
Blankets, heat, and why free energy has not illuminated the workings of the brain
Donald Spector1, Daniel Graham2
1Department of Physics, Hobart and William Smith Colleges, Geneva, NY 14456, USAspector@hws.eduhttp://people.hws.edu/spector/.
Abstract:
What can we hope to learn about brains from the free energy principle? In adopting the "primordial soup" physical model, Bruineberg et al. perpetuate the unsupported notion that the free-energy principle has a meaningful physical - and neuronal - interpretation. We examine how minimization of free energy arises in physical contexts, and what this can and cannot tell us about brains.
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