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Updated: Aug 27, 2025

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
The relationship between mean platelet volume and the mortality of patient severe head trauma; first study
Hizir Kazdal1, Ayhan Kanat2, Bulent Ozdemir2
1Medical Faculty, Department of Anesthesiology and Reanimation, Recep Tayyip Erdogan University, Rize, Turkey.
Background:
Prediction of mortality in a patient with head trauma is essential. In this study, the effect of mean platelet volume (MPV) on the mortality rate of patients with severe head trauma was studied.
Material And Methods:
The relationship between mortality and mean platelet volumes of patient with cranial trauma was retrospectively analyzed.
Results:
43 patients with head trauma were admitted to the intensive care unit during the study period. While 17 patients died (Group I), 26 patients survived (Group II). Cox regression analysis showed that late MPV (at exitus or discharged date), WBC at admission, and age increase the mortality rate 1,770, 1,202, 1,052 times, respectively.
Conclusions:
The present study shows that MPV may be a useful predictor of mortality in patients with severe head trauma.

