Multimodality imaging appearance of intrapericardial paragangliomas

Area of Science:

• Cardiovascular Pathology
• Neuroendocrinology
• Oncology

Background:

• Paragangliomas are rare neuroendocrine tumors arising from neural crest cells.
• Intrapericardial paragangliomas, originating from intrinsic cardiac ganglia, are exceptionally rare, accounting for less than 1% of cardiac tumors.
• These tumors can occur in the posterior atria, atrioventricular groove, and along the great vessels.

Purpose of the Study:

• To describe the characteristics, demographics, presentation, diagnosis, pathology, management, and outcomes of intrapericardial paragangliomas.
• To present the largest reported case series of intrapericardial paragangliomas.
• To emphasize the role of multimodality imaging in diagnosing these rare tumors.

Main Methods:

• Retrospective review of 11 patients with intrapericardial paragangliomas.
• Analysis of clinical data, including demographics, symptoms, and treatment.
• Correlation of histopathological findings with imaging characteristics.

Main Results:

• The study analyzed 11 patients with intrapericardial paragangliomas.
• Detailed characteristics, diagnostic methods, and management strategies were elucidated.
• Multimodality imaging findings were highlighted for their diagnostic utility.

Conclusions:

• Intrapericardial paragangliomas are rare but distinct neuroendocrine tumors.
• Multimodality imaging plays a crucial role in their diagnosis.
• This case series provides valuable insights into the management and outcomes of these tumors.