Implications of racial/ethnic perinatal health inequities on long-term neurodevelopmental outcomes and health services utilization
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Updated: Aug 27, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Yarden S Fraiman1, Alejandra Barrero-Castillero1, Jonathan S Litt2
1Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA; Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Insights
Preterm birth and low birth weight increase neurodevelopmental risks. Inequities in care access may worsen long-term outcomes for diverse infants, necessitating targeted research and interventions.
Area of Science:
- Neurodevelopmental science
- Public health
- Health equity
Background:
- Infants born preterm with low birth weight face higher risks for motor, cognitive, speech, and social challenges compared to term-born infants.
- Existing research shows disparities in preterm birth and short-term health issues across racial, ethnic, linguistic, and nativity groups.
- Limited understanding exists regarding how these disparities impact long-term neurodevelopmental outcomes.
Approach:
- This review synthesizes current knowledge on the effects of race, ethnicity, nativity, and language on long-term outcomes for preterm infants.
- It presents a framework for analyzing these inequities within broader social, political, and historical contexts.
- The review also offers recommendations for future research, interventions, and advocacy.
Key Points:
- Disparities in access to post-discharge support services for preterm infants are a significant concern.
- Unequal access may exacerbate existing gaps in health, development, and overall functioning.
- Understanding the influence of social determinants is crucial for addressing neurodevelopmental inequities.
Conclusions:
- Further research is needed to identify specific mechanistic pathways driving these long-term outcome disparities.
- Developing targeted interventions is essential to eliminate inequities in neurodevelopmental outcomes.
- Advocacy and policy changes are critical to ensure equitable support and opportunities for all preterm infants.
Abstract:
Infants born preterm and with low birth weight have increased risk for neurodevelopmental challenges later in life compared to term-born peers. These include functional motor impairment, cognitive and speech delays, neurobehavioral disorders, and atypical social development. There are well-documented inequities in the population distributions of preterm birth and associated short-term morbidities by race, ethnicity, language, and nativity. Far less is known about how these inequities affect long-term outcomes, though the impact of unequal access to post-discharge support services for preterm infants raises concerns about widening gaps in health, development, and functioning. In this review, we describe what is currently known about the impact of race, ethnicity, nativity, and language on long-term outcomes. We provide a framework for understanding inequities in social, political, and historical context. And we offer guidance for next steps to delineate mechanistic pathways and to identify interventions to eliminate inequities in long-term neurodevelopmental outcomes through research, intervention, and advocacy.
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