Implications of racial/ethnic perinatal health inequities on long-term neurodevelopmental outcomes and health

Yarden S Fraiman1, Alejandra Barrero-Castillero1, Jonathan S Litt2

  • 1Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA; Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Seminars in Perinatology
|September 29, 2022
PubMed

Insights

Preterm birth and low birth weight increase neurodevelopmental risks. Inequities in care access may worsen long-term outcomes for diverse infants, necessitating targeted research and interventions.

Area of Science:

  • Neurodevelopmental science
  • Public health
  • Health equity

Background:

  • Infants born preterm with low birth weight face higher risks for motor, cognitive, speech, and social challenges compared to term-born infants.
  • Existing research shows disparities in preterm birth and short-term health issues across racial, ethnic, linguistic, and nativity groups.
  • Limited understanding exists regarding how these disparities impact long-term neurodevelopmental outcomes.

Approach:

  • This review synthesizes current knowledge on the effects of race, ethnicity, nativity, and language on long-term outcomes for preterm infants.
  • It presents a framework for analyzing these inequities within broader social, political, and historical contexts.
  • The review also offers recommendations for future research, interventions, and advocacy.

Key Points:

  • Disparities in access to post-discharge support services for preterm infants are a significant concern.
  • Unequal access may exacerbate existing gaps in health, development, and overall functioning.
  • Understanding the influence of social determinants is crucial for addressing neurodevelopmental inequities.

Conclusions:

  • Further research is needed to identify specific mechanistic pathways driving these long-term outcome disparities.
  • Developing targeted interventions is essential to eliminate inequities in neurodevelopmental outcomes.
  • Advocacy and policy changes are critical to ensure equitable support and opportunities for all preterm infants.

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