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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
Ultrasonographic prediction model for benign and malignant salivary gland tumors: a preliminary study
LiuQing Peng1, Nan Li1, YuKun Luo1
1Department of Ultrasound, the First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Objective:
To establish an ultrasonographic (US) prediction model for benign and malignant salivary gland tumors.
Study Design:
We retrospectively analyzed the clinical data of 575 patients with salivary gland tumors. Patients were divided into benign (N = 420) and malignant (N = 155) tumor groups based on histopathologic results. The clinical and US features of the tumor groups were statistically compared. With histopathologic findings as the dependent variable and clinical and US features as independent variables, a multiple logistic regression model was established. The area under the receiver operating characteristic curve (AUC) was calculated to evaluate its diagnostic efficacy.
Results:
Statistically significant differences between tumor groups were discovered for patient age, tumor site, and the US features of tumor size, shape, and margins; posterior echo pattern; microcalcification, abnormal lymph nodes, and tumor vascularity. Individual US features had limited diagnostic value. The AUC, sensitivity, specificity, and accuracy values of the logistic regression equation were 0.893, 84.3%, 80.0%, and 83.1%, respectively.
Conclusion:
The diagnostic performance of the predictive model was significantly better than that of any single US factor. This suggests that establishment of multiple models based on US features can improve the accuracy of diagnosis of benign and malignant salivary gland tumors and can be applied clinically.
