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Updated: Aug 27, 2025
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
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An unusual ileocecal tumor
Takato Inoue1, Naonori Inoue1, Takuji Kawamura1
1Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
Oxford Medical Case Reports
|September 30, 2022
Summary
This case report details a rare instance of diffuse large B-cell lymphoma (DLBCL) presenting as an ileocecal fistula. The diagnosis was confirmed after imaging and endoscopic evaluation revealed an unusual outpouching.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
- Gastrointestinal involvement in DLBCL can manifest in various ways, but fistulas are uncommon.
- Ileocecal fistulas typically arise from inflammatory bowel disease or complications of surgery.
Observation:
- A 57-year-old male presented with abdominal pain.
- Abdominal CT revealed ileocecal region wall thickening.
- Lower gastrointestinal endoscopy identified an ileocecal fistula, with no visible tumor at the ileocecal valve.
Findings:
- The patient was diagnosed with diffuse large B-cell lymphoma (DLBCL).
- The DLBCL manifested as a fistula between the ileum and the cecum.
- Endoscopic and imaging findings were crucial in diagnosing this rare presentation.
Implications:
- This case highlights the importance of considering lymphoma in the differential diagnosis of unexplained gastrointestinal fistulas.
- Early recognition and diagnosis of DLBCL with unusual presentations are critical for timely treatment.
- Further research into the pathogenesis and management of gastrointestinal DLBCL with fistula formation is warranted.
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