Related Experiment Video

Updated: Jul 23, 2026

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

15.0K

Peutz-Jeghers syndrome revealed by recurrent small bowel intussusceptions in children: A case report

Chtourou Rahma1, Ben Kraiem Najoua1, Zouari Mohamed1

  • 1Department of Pediatric Surgery, Hedi Chaker Hospital University of Sfax Sfax Tunisia.

Clinical Case Reports
|September 30, 2022
PubMed

Insights

Peutz-Jeghers syndrome, a rare condition, can cause life-threatening bowel intussusceptions. This case highlights jejunal polyps as a cause in a young girl, requiring surgical intervention.

Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Clinical Genetics

Background:

  • Peutz-Jeghers syndrome (PJS) is an inherited disorder characterized by hamartomatous polyps in the gastrointestinal tract and mucocutaneous pigmentation.
  • PJS significantly increases the risk of gastrointestinal cancers and other malignancies.
  • Early diagnosis and management are crucial for improving patient outcomes.

Observation:

  • A young female patient presented with recurrent episodes of small bowel intussusception.
  • Surgical exploration revealed numerous jejunal polyps as the underlying cause of the intussusceptions.
  • The polyps were successfully removed through mini enterotomies.

Findings:

  • Pathological examination confirmed the presence of hamartomatous polyps consistent with Peutz-Jeghers syndrome.
  • The jejunal polyps were identified as the direct cause of the jejunojejunal intussusceptions.
  • This case underscores the presentation of PJS in pediatric patients.

Implications:

  • This case highlights the importance of considering Peutz-Jeghers syndrome in pediatric patients with recurrent intussusceptions.
  • Timely surgical intervention for polyps can prevent complications associated with intussusception.
  • Genetic counseling and long-term surveillance are essential for individuals diagnosed with PJS.

Keywords:
Peutz–Jeghers syndromechildrenintussusception

More Related Videos

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.505:45

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Published on: April 26, 2019

13.5K
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

1.4K

Related Concept Videos

Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...