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Radiological Features of Zollinger-Ellison Syndrome: A Report of Two Cases
Thara Pratap1, Muhammed Jasim Abdul Jalal2, Dhanya Jacob1
1Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India.
Zollinger-Ellison syndrome (ZES) is a rare condition caused by excess gastrin. This summary highlights two patient cases presenting with severe abdominal pain, vomiting, diarrhea, and weight loss, characteristic of ZES.
Area of Science:
- Endocrinology
- Gastroenterology
- Oncology
Background:
- Zollinger-Ellison syndrome (ZES) is a rare clinical condition.
- It is characterized by hypersecretion of gastrin from duodenal or pancreatic gastrinomas.
- ZES can be sporadic or associated with multiple endocrine neoplasia type 1, typically manifesting in adults aged 20-50.
Purpose of the Study:
- To describe two cases of Zollinger-Ellison syndrome.
- To highlight the presenting symptoms of abdominal pain, vomiting, watery diarrhea, and significant weight loss.
Main Methods:
- Case report presentation.
- Clinical data review of two patients diagnosed with ZES.
Main Results:
- Two patients presented with a constellation of symptoms including abdominal pain, vomiting, watery diarrhea, and substantial weight loss.
- These symptoms are consistent with the clinical presentation of Zollinger-Ellison syndrome.
Conclusions:
- Zollinger-Ellison syndrome requires a high index of suspicion due to its rarity and varied presentation.
- Early diagnosis and management are crucial for patients presenting with severe gastrointestinal symptoms suggestive of ZES.
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